Referenzen Moderne orale Substanzen A-Z
- Swissmedic Arzneimittelinformation
- Pleyer L, Greil R. Arzneimittelprofil Dasatinib. Medizin Medien Austria. November 2007
- Li J, Uhao M, He P et al. Differential Metabolism of Gefitinib and Erlotinib by Human Cytochrome P450 Enzymes. Clin Canc Res 2007; 13: 3731-3737
- Eickhoff C, Schulz M. Imatinib, ein Tyrosinkinase-Inhibitor. Pharmazeutische Zeitschrift online 2003. Ausgabe 19
- Rumpold H, Gastl G, Wolf D. Arzneimittelprofil Nilotinib. Medizin Medien Austria. März 2008
- Bhojani N et al. Toxicities Associated with the Administration of Sorafenib, Sunitinib and Temsirolimus and Their Management. 2008; 53: 917-930
- Greil R, Micksche M. Arzneimittelprofil Sorafenib. Medizin Medien Austria. Dezember 2006
- Schmidinger M, Loidl W. Arzneimittelprofil Sunitinib. Medizin Medien Austria. April 2007
- Übersetzung der australischen Produktinformation zu Thalidomide Pharmion 50 mg Hartkapseln. Version 1, 23. August 2004
- Europäische Fachinformation Thalidomide: http://www.emea.europa.eu/humandocs/Humans/EPAR/thalidomidecelgene/thalidomidecelgene.htm
- Marty M, Fumoleau P, Adenis A et al. Oral vinorelbine pharmacokinetics and absolute bioavailability study in patients with solid tumors. Ann Oncol 12: 1643-1649, 2001
- Nguyen L, Tranchand B, Puozzo C et al. Population pharmacokinetics model and limited sampling strategy for intravenous vinorelbine derived from phase I clinical trial. Clin Pharmacol. 53, 459-468.
- Yeh ETH, et al. Cardiovascular Complications of Cancer Therapy Incidence, Pathogenesis, Diagnosis, and Management J Am Coll Cardiol 2009; 53: 2231–47
- Van Cutsem E, Hoff PM, Blum JL, Abt M, Osterwalder B. Incidence of cardiotoxicity with the oral fluoropyrimidine capecitabine is typical of that reported with 5-fluorouracil. Ann Oncol 2002;13:484 –5.
- Kosmas C, Kallistratos MS, Kopterides P, et al. Cardiotoxicity of fluoropyrimidines in different schedules of administration: a prospective study. J Cancer Res Clin Oncol 2008; 134: 75– 82.
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- Cardinale D, Colombo A, Colombo N. Acute coronary syndrome induced by oral capecitabine. Can J Cardiol 2006; 22: 251–3.
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- Schnetzler B, Popova N, Collao Lamb C, Sappino AP. Coronary spasm induced by capecitabine. Ann Oncol 2001; 12: 723– 4.
- Frickhofen N, Beck FJ, Jung B, Fuhr HG, Andrasch H, Sigmund M. Capecitabine can induce acute coronary syndrome similar to 5-fluorouracil. Ann Oncol 2002; 13: 797– 801.
- Arbea L, Coma-Canella I, Martinez-Monge R, Garcia-Foncillas J. A case of capecitabine-induced coronary microspasm in a patient with rectal cancer. World J Gastroenterol 2007; 13: 2135–7.
- Sestito A, Sgueglia GA, Pozzo C, et al. Coronary artery spasm induced by capecitabine. J Cardiovasc Med (Hagerstown) 2006; 7: 136–8.
- Papadopoulos CA, Wilson H. Capecitabine-associated coronary vasospasm: a case report. Emerg Med J 2008; 25: 307–9.
- Deitcher SR, Gomes MP. The risk of venous thromboembolic disease associated with adjuvant hormone therapy for breast carcinoma: a systematic review.
- Kedar RP, Bourne TH, Powles TJ, Collins WP, Ashley SE, Cosgrove DO, Campbell S. Effects of tamoxifen on uterus and ovaries of postmenopausal women in a randomised breast cancer prevention trial. Lancet. 1994 May 28;343(8909):1318-21.
- Braithwaite RS, Chlebowski RT, Lau J, George S, Hess R, Col NF. Meta-analysis of vascular and neoplastic events associated with tamoxifen. J Gen Intern Med. 2003 Nov;18(11):937-47.
- Diesing D, Friedrich M, von Otte S. Nebenwirkungen der endokrinen Therapie beim Mammakarzinom. Gynäkologische Endokrinologie 2005 (3):91-96.
- Vandewiele B, Vandecasteele SJ, Vanwalleghem L, De Vriese AS. Diffuse alveolar hemorrhage induced by everolimus. Chest. 2010 Feb;137(2):456-9.
- Aparicio G, Calvo MB, Medina V, Fernandez O, Jimenez P, Lema M, et al. Comprehensive lung injury pathology induced by mTOR inhibitors. Clin Transl Oncol. 2009 Aug;11(8):499-510.
- Otton J, Hayward CS, Keogh AM, Glanville AR, Macdonald PS. Everolimus-associated pneumonitis in 3 heart transplant recipients. J Heart Lung Transplant. 2009 Jan;28(1):104-6.
- Rodriguez-Moreno A, Ridao N, Garcia-Ledesma P, Calvo N, Perez-Flores I, Marques M, et al. Sirolimus and everolimus induced pneumonitis in adult renal allograft recipients: experience in a center. Transplant Proc. 2009 Jul-Aug;41(6):2163-5.
- Exposito V, Vasquez de Prada JA, Gomez-Roman JJ, Gonzalez-Vilchez F, Llano-Cardenal M, Garcia-Camarero T, et al. Everolimus-related pulmonary toxicity in heart transplant recipients. Journal of Heart and Lung Transplantation. 2008;27(7):797-800.
- David S, Kumpers P, Shin H, Haller H, Fliser D. Everolimus-associated interstitial pneumonitis in apatient with a heart transplant. Nephrology Dialysis Transplantation 2007; 22: 3363-3364.
- Tyverb EPAR Procuct Information
- Tykerb (Lapatinib) U.S. Prescribing Information
- Yeh ETH, Bickford CL. Cardiovascular Complications of Cancer Therapy:Incidence, Pathogenesis, Diagnosis, and Management. J Am Coll Cardiol 2009;53:2231–47.
- Mellor HR, Bell AR, Valentin J-P et al. Cardiotoxicity associated with targeting kinase pathways in cancer. Toxicol. Sci. (2011) 120 (1): 14-32.
- Je, YMS et al.: Risk of bleeding with vascular endothelial growth factor receptor tyrosine-kinase inhibitors sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials. The Lancet Oncology 2009, 10(10):967-974
- Hamnvik OP, Larsen PR, Marqusee E.
J Natl Cancer Inst. 2011 Nov 2;103(21):1572-87. Epub 2011 Oct 18 - Zelboraf Drug Approval Package, Medical Review Nov 30, 2011
- Torben K. Becker; Sai-Ching J. Yeung. Drug-induced QT interval prolongation in cancer Patients. Oncol Rev 2010
- Langmuir P B, Yver A. Vandetanib for the Treatment of Thyroid Cancer. Clinical Pharmacology & Therapeutics 91, 71-80 doi:10.1038/clpt.2011.272
- Zelboraf Full Prescribing Information. Reference ID 3001518
- Langmuir P B, Yver A. Vandetanib for the Treatment of Thyroid Cancer. Clinical Pharmacology & Therapeutics 91, 71-80 doi:10.1038/clpt.2011.272
- Demetri GD et al. Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial. Lancet 2013; 381 (9863): 295-302
- Grothey A et al. Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial. Lancet 2013; 381: (9863): 303-312
- L. Albiges, F. Chamming’s, B. Duclos et al. Incidence and management of mTOR inhibitor-associated pneumonitis in patients with metastatic renal cell carcinoma. Annals of Oncology. 2012; 00: 1-11
Interaktionen
- Arzneimittelkompendium der Schweiz
- Kämmerer W. Klinisch relevante pharmakokinetische Interaktionen von und mit Zytostatika. Arzneimitteltherapie 2008; 26. Jahrgang, Heft 2: 51-61
- Pleyer L, Greil R. Arzneimittelprofil Dasatinib. Medizin Medien Austria. November 2007
- Li J, Uhao M, He P et al. Differential Metabolism of Gefitinib and Erlotinib by Human Cytochrome P450 Enzymes. Clin Canc Res 2007; 13: 3731-3737
- Eickhoff C, Schulz M. Imatinib, ein Tyrosinkinase-Inhibitor. Pharmazeutische Zeitschrift online 2003. Ausgabe 19
- Drucker BJ, Sawyers CL, Capdeville R et al. Chronic myeloid leukemia. Hematology 2001: 87-112
- Rumpold H, Gastl G, Wolf D. Arzneimittelprofil Nilotinib. Medizin Medien Austria. März 2008
- Greil R, Micksche M. Arzneimittelprofil Sorafenib. Medizin Medien Austria. Dezember 2006
- Schmidinger M, Loidl W. Arzneimittelprofil Sunitinib. Medizin Medien Austria. April 2007
- Übersetzung der „Product Information” (Produktinformation) zu Thalidomide Pharmion 50 mg Hartkapseln, Version 1, 23. August 2004
- Thalomid (thalidomide) Capsules. Revised Package Insert, 15 July 1998
- Fattinger K, Roos M, Vergeres P et al. Epidemiology of drug exposure and adverse drug reaction in two Swiss departments of internal medicine. Br J Clin Pharmacol 2000; 499: 158-167
- Zoppi M, Braunschweig S, Kuenzi UP et al. Incidence of lethal adverse drug reactions in the comprehensive hospital drug monitoring, a 20-year survey, 1974-1993, based on the data of Berne/St. Gallen. Eur J Clin Pharmacol 2000; 56: 427-430
- Beijnen JH, Schellens JH. Drug interactions in oncology. Lancet Oncol 2004; 5: 489-496
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- McLeod HL. Clinically relevant drug-drug interactions in oncology. Br J Clin Pharmacol 1998; 45: 539-544
- Lam MSH, Ignoffo RJ. A guide to clinically relevant drug interactions in oncology. J Oncol Pharm Practice 2003; 9: 45-85
- Kämmerer W. Klinisch relevante pharmakokinetische Interaktionen von und mit Zytostatika. Arzneimitteltherapie 2008; 26. Jahrgang, Heft 2: 51-61
- Benet LZ, Hoener BA. Changes in plasma protein bindings have little clinical relevance. Clin Pharmacol Ther 2002; 71: 115-121
- Ingelman-Sundberg M. Genetic polymorphisms of cytochrome P450-2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity. Pharmacogenomics J 2005: 56-63
- Zagermann-Muncke P. Wenn Arzneistoffe die Transportproteine beeinflussen. PZ Pharmazeutische Zeitung online 2006; 50
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- Marty M, Fumoleau P, Adenis A et al. Oral vinorelbine pharmacokinetics and absolute bioavailability study in patients with solid tumors. Ann Oncol 12: 1643-1649, 2001
- Nguyen L, Tranchand B, Puozzo C et al. Population pharmacokinetics model and limited sampling strategy for intravenous vinorelbine derived from phase I clinical trial. Clin Pharmacol. 53, 459-468.
Unerwünschte Wirkungen und Behandlungsvorschläge
- Bhojani N et al. Toxicities Associated with the Administration of Sorafenib, Sunitinib and Temsirolimus and Their Management. 2008; 53: 917-930
- Wood LS. Managing the side effects of sorafenib and sunitinib. Community Oncology, Sept. 2006; 3: 558-562
- Grünwald V, Heinzer H, Fiedler W. Managing side effects of angiogenesis inhibitors in renal cell carcinoma. Onkologie 2007; 30: 519-524
- Négrier S, Ravaud A. Optimisation of sunitinib therapy in metastatic renal cell carcinoma: adverse-event management. Eur J Canc 2007; Supp 5. No. 7: 12-19
- Kollmannsberger C, Soulieres D, Wong R et al. Sunitinib therapy for metastatic renal cell carcinoma: recommendations for management of side effects. Can Urol Ass J 2007; 1: 41-54
- Cancer-Related Fatigue. NCCN Practice Guidelines in Oncology. V. 1. 2008
- Wilson KG, Chochinov HM, Skirko MG et al. Depression and anxiety disorders in palliative cancer care. J Pain Symptom Manage 2007; 33: 118-129
- NCCN Practice Guidelines in Oncology
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- Sica DA. Angiogenesis inhibitors and hypertension: an emerging issue. J Clin Oncol 2006; 24: 1329-1331
- Link H. Anämie bei Krebs. Diagnostik, Therapie, Transfusionen, Erythropoese stimulierende Agentien, Eisensubstitution. Onkologe 2009; 15: 129-141
- Auerbach M, Silberstein PS, Webb T et al. Darbepoetin alfa (da) 500 mcg or 300 mcg once every three weeks (q3w) with or without iron in patients (pts) with chemotherapy-induced anemia. Ann Oncol 2008; Volume 19, Supplement 8
- Auerbach M, Ballard H, Trout JR et al. Intravenous iron optimizes the response to recombinant human erythropoietin in cancer patients with chemotherapy-related anemia: a multicenter, open-label, randomized trial. J Clin Oncol 2004; 22: 1301-1307
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- Hedenus M, Birgegard G, Nasman P et al. Addition of intravenous iron to epoetin beta increases hemoglobin response and decreases epoetin dose requirement in anemic patients with lymphoproliferative malignancies: a randomized multicenter study. Leukemia 2007; 21: 627-632
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- Pedrazzoli P, Farris A, Del Prete S et al. Randomized trial of intravenous iron supplementation in patients with chemotherapy-related anemia without iron deficiency treated with darbepoetin alfa. J Clin Oncol 2008; 26: 1619-1625
- Schmidinger M, Loidl W. Arzneimittelprofil Sunitinib. Medizin Medien Austria. April 2007
- Benson AB, Ajani JA, Catalano RB et al. Recommended guidelines for the treatment of cancer treatment-induced diarrhea. J Clin Oncol 2004; 22: 2918-26
- Schmidinger M. Oncology Update Symposium: Krebsmanagement in der modernen Onkologie. Zürich 11. September 2008
- Ginger (Zingiber officinale Roscoe)
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- OFSP (Office fédéral de la santé publique)
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- American Society of Clinical Oncology (ASCO)
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