Chairs: Josep Tabernero, MD, PhD and Eric Van Cutsem, MD, PhD
Updates on CALGB/SWOG 80405: Alan P. Venook, MD
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Discussant: When clinical trials are practice changing
Alberto Sobrero, MD
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SIRFLOX: Randomized trial comparing first-line mFOLFOX6 ± bevacizumab versus mFOLFOX6 + selective internal radiation therapy (SIRT) ± bevacizumab in patients with metastatic colorectal cancer (mCRC) – analysis by presence or absence of extra-hepatic metastases and bevacizumab treatment: Guy van Hazel, et al., O-019
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Discussant
Dirk Arnold, MD
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Quality-of-life results from RAISE Randomized, double-blind phase III study of FOLFIRI plus ramucirumab or placebo in patients with metastatic colorectal carcinoma after first-line therapy with bevacizumab, oxaliplatin, and a fluoropyrimidine: Rocio Garcia-Carbonero, et al., O-020
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Cetuximab beyond progression in RAS wild type (WT) metastatic colorectal cancer (mCRC): the CAPRI-GOIM randomized phase II study of FOLFOX versus FOLFOX plus cetuximab: Fortunato Ciardiello, et al., LBA-09
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Discussant: How to choose between the different biologics in 2nd line
Michel Ducreux, MD, PhD
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Updated Results of the MEK inhibitor trametinib (T), BRAF inhibitor dabrafenib (D), and anti-EGFR antibody panitumumab (P) in patients (pts) with BRAF V600E mutated (BRAFm) metastatic colorectal cancer (mCRC): Eric Van Cutsem et al., LBA-07
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Results of a phase 1b study of the selective BRAF V600 inhibitor encorafenib in combination with cetuximab alone or cetuximab+alpelisib for treatment of patients with advanced BRAF-mutant metastatic colorectal cancer: Elena Elez et al., LBA-08
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Discussant: What to do in BRAF mutant CRC patients?
Ramon Salazar Soler, MD
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The ESMO consensus on metastatic CRC – 2015
Eric Van Cutsem, MD, PhD, Dirk Arnold, MD, and Andrés Cervantes, MD, PhD
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