Startseite Kongressberichte 2021 63rd ASH Annual Meeting and Exposition In-Person/Virtual Lymphoma Aggressive Lymphomas: Clinical and Epidemiological Clinical Management of Aggressive B cell NHL

627. Aggressive Lymphomas: Clinical and Epidemiological: Clinical Management of Aggressive B cell NHL

451
Combining PET Radiomic Features with MYC Gene Rearrangement Results in High Prediction of Outcome in Diffuse Large B-Cell Lymphoma

Jakoba J Eertink, Gerben J.C Zwezerijnen, Sanne E Wiegers, et al.

According to the authors, radiomics features can increase the efficiency of clinical trials by only selecting poor prognosis patients. See more info in the abstract.

 

452
Early Integration of High Dose Methotrexate to Frontline DLBCL Therapy Does Not Impact CNS Relapse Compared to End of Treatment Delivery: A Multicentre International Analysis of 1384 Patients

Matthew R Wilson, Toby A. Eyre, Amy A Kirkwood, et al.

In this extensive analysis of 1L R-CHOP patients, no evidence was found that EOT administration increased the risk of CNS relapse compared to i-HDMTX. See more info in the abstract.

 

453
Prognostic Factors Other Than Age Drive the Risk of Disease Progression in Adults with Burkitt Lymphoma Treated with DA-EPOCH-R

Rahul Lakhotia, Kieron Dunleavy, Jeremy S. Abramson, et al.

Excellent 5-year TTP (95%) and EFS (94%) were found in the multicenter NCI 9177 study in patients with Burkitt lymphoma and low- or medium-risk BL-IPI scores. Age is not prognostic with DA-EPOCH-R. In contrast, CNS /BM /PB involvement is prognostic in the BL-IPI groups.

 

454
Risk of Incident Diabetes and Dysregulated Pre-Existing Diabetes Mellitus in Newly Diagnosed Lymphoma Patients Treated with Steroid-Containing Immunochemotherapy: A Danish Population-Based Study

Joachim Baech, Marianne Tang Severinsen, Andreas Kiesbye Øvlisen, et al.

Beyond the first year, patients treated with steroid-containing immunochemotherapy did not show a higher risk of DM than comparable comparator products. See more info in the abstract.

 

455
High-Grade B-Cell Lymphoma, Not Otherwise Specified (HGBL, NOS): Characteristics, Treatment, and Outcomes from 17 Academic US Centers

Adam Zayac, Daniel J Landsburg, Mitchell Hughes, et al.

See more info in the abstract

 

456

A Randomized Placebo-Controlled Trial of Primary Prophylaxis with Weekly Alendronate Against Glucocorticoid-Induced Osteoporosis in Lymphoma Patients Treated with Steroid-Containing Chemotherapy.

Paw Jensen, Lasse H. Jakobsen, Martin Bøgstede, et al.

For primary prophylaxis against glucocorticoid-induced osteoporosis in all lymphoma patient subgroups, alendronate has been shown to be clinically important, safe, and effective, with the greatest effect size in women.