Startseite Drugs oral & i.v., Guidelines, Interaktionen The Cancer Cell Line Encyclopedia

First volume of the Cancer Cell Line Encyclopedia

Academic-industry collaboration yields comprehensive encyclopedia of genetic and molecular information and enables predictive modelling of anticancer drug sensitivity.

The Cancer Cell Line Encyclopedia (CCLE) project is a collaboration between the Broad Institute, and the Novartis Institutes for Biomedical Research and its Genomics Institute of the Novartis Research Foundation to conduct a detailed genetic and pharmacologic characterization of a large panel of human cancer models, to develop integrated computational analyses that link distinct pharmacologic vulnerabilities to genomic patterns and to translate cell line integrative genomics into cancer patient stratification. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression and mutation data for about 1000 cell lines.


CCLE Website